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Bio-Techne corporation
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Bio-Techne corporation
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GenTech Scientific Inc
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Molecular oxygen O2 is essential for mammalian metabolic processes such as oxidative phosphorylation Thus survival depends upon instantaneous transcriptional modulation of genes that maintain O2 homeostasis Transcriptional control of several of these genes is mediated
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BACKGROUND Hypoxia-inducible factor-1 (HIF-1) is a dimeric transcriptional complex that has been recognized primarily for its role in the maintenance of oxygen and energy homoeostasis. It consists of two basic helix-loop-helix proteins of the PAS
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